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PubMed Clayton, A.H., Kingsberg, S.A., Goldstein, I., Baskin, L., Kim, N.N., Volkmann, E.R., Simon, J.A., Higgins, K.S., Jordan, R., & Portman, D.J

Comparative study of the neurotoxicological effects of tramadol and tapentadol in SH-SY5Y cells

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This study received an exemption from the Institutional Review Board of the Boston University School of Medicine, as it exclusively utilized postmortem tissue samples, which are not classified as human subjects under regulatory guidelines

5.1.1.2 Catalase (CAT) Catalase (CAT), primarily found in the peroxisomes, is a ubiquitous antioxidant enzyme that catalyzes the transformation of H 2 O 2 into water and oxygen (Fig