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BioMed research international, 2019, 8086257

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Do not reconstitute a vial straight from the freezer

Based on the here-presented biochemical, structural and computational evidence, we propose that arGSTs utilize a GSH-dependent Brnsted base mechanism for conversion of the semi-stable LDOX product flavan-3,3,4-triol ( 4 ) or flavan-3-on-4-ol ( 7 ) into flav-2-en-3,4-diol ( 8 -B4), the 4-hydration species of cyanidin ( 8 ) (Extended Data Fig

DSIP may also stimulate the endogenous antioxidant system, influencing various enzymatic levels