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PMID: 17179228

Researchers have found that human proximal tubule epithelial cell lines exhibited distinct ultrastructural alterations indicative of pyroptosis when exposed to high glucose, and that the expression of TLR4, NLRP3, caspase-1, GSDMD-N, IL-1, and IL-18 are significantly upregulated (124)

Kojic Acid Can Irritate Your Skin: Kojic acid may cause your skin to redden, burn, peel, or feel dry

Zeratsky, K., & Mayo Clinic

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