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BPC-157 modulates nitric oxide synthase pathways by selectively reducing inducible NOS (iNOS) expression, which normally inhibits gastric smooth muscle contraction, while preserving endothelial NOS needed for vascular function

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Thus, this modest increase in LDL-C may be misleading regarding ASCVD risk, as patients with obesity may have a higher concentration of atherogenic small, dense LDL particles, and therefore high levels of apoB for a given blood LDL-C [10, 13]

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