Acta Endocrinol 121:101106 Hirschberg R, Kopple JD (1989) Evidence that insulin-like growth factor I increases renal plasma flow and glomerular filtration rate in fasted rats
and data triangulation
That worry is real and common
Liu N, Wu WL, Wan XR, Wang J, Huang JN, Jiang YY, et al
In rat tendon studies, administration accelerated outgrowth, fibroblast migration, and post-injury cellular survival (PMID 21030672)
Commonly Reported Side Effects Fatigue or lethargy (typically within the first week) Headaches or mild brain fog Dizziness or a drop in blood pressure Temporary injection site irritation Increased thirst or urination Some users report vivid dreams or changes in sleep patterns, though this is more common with compounds like MK-677 and HGH