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Biomaterials 83 , 156168 (2016)

The tradeoff: more receptor targets mean more potential side effects

In some cases, a lower maintenance dose may be chosen if it achieves weight loss with minimal side effects

Control targets Achieving good glycemic control may avoid or delay the appearance of micro- and macrovascular complications, as has been shown by different studies involving long periods of follow-up.11 It is therefore recommended that very strict control should be achieved in the early stages of diabetes management (glycosylated hemoglobin [HbA1c] 8.5% in symptomatic patients

Sirmirelin is a synthetic compound

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