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Conjugating water-insoluble toxins (heavy metals, xenobiotics, drug metabolites) to make them excretable through bile or urine

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Blood Sugar Fluctuations If semaglutide is used alongside other glucose-lowering medications like metformin, your blood sugar may dip too low (hypoglycemia), causing symptoms of low blood sugar like blurred vision, shakiness, or dizziness

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Whilst cold sensations were reported by some participants in that trial, precise incidence figures for 'feeling cold' as a discrete adverse event are not available in the published data , and robust population-level frequency data have not yet been established