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methanolic extract was reported to have very strong effects in ameliorating liver functions after APAP treatment (750 mg/kg) potentially by antioxidant properties that the mean liver ALT and AST levels were even lower in the pomegranate peel posttreatment group after APAP treatment (ALT, 49.6 12.1

On the other hand, autophagy leads to a significant decrease in intracellular GSH levels and vice versa 67

The absorption rate is slightly decreased with food, however, taking it with a meal prevents gastrointestinal distress

While the early data is exciting, it has not yet been approved for medical use and is only available through clinical studies