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Description

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Because the information provided was often limited and because these events can be influenced by other potential factors, we determined that the information in these reports did not demonstrate a clear relationship with the use of GLP-1 receptor agonists. The agency emphasized that it would continue looking into this issue, because it could not definitively rule out that a small risk may exist. Additional details from the FDA about GLP-1 receptor agonists The FDA emphasized in its assessment that patients prescribed GLP-1 drugs should not abruptly stop taking them without consulting a professional

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Participants were adults with: Obesity (BMI 30 kg/m) or Overweight (BMI 27 kg/m) with at least one weight-related comorbidity such as hypertension, dyslipidemia, obstructive sleep apnea, or cardiovascular disease No diabetes diagnosis Participants were randomized 1:1 to receive either: Maximum tolerated dose of Zepbound (10 mg or 15 mg) Maximum tolerated dose of Wegovy (1.7 mg or 2.4 mg) The study cohort had a mean age of 44.7 years, 64.7% were women, and participants had an average body weight of 249 pounds with a mean BMI of 39.4 kg/m

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