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Autophagy and the proteasome Large intracellular particles, including damaged mitochondria and protein aggregates, are degraded by a process known as autophagy

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Diabetes 12 , 1179551419875453 (2019)

Additionally, loss of Epo, which may directly protect renal cells from injury [109,110], may devastate renal damage in Epo-deficient anemic mice

On the other hand, RNA-seq, in situ hybridization, or GLP-1R antisera analysis showed no to low expression of GLP-1R in hepatocytes, skeletal myocytes, and adipocytes (Figures 5, 6)

Synthetic drugs designed to target key signaling pathways in the gut effectively reduce blood glucose levels and restore insulin signaling