Part of the solution is to use methylated B12 and folate, rather than folic acid
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Additionally, MB was shown to photo-inactivate bacteria in 1928 [20], and its potent antiviral effects were discovered soon after [21]
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The translation to the bedside of this therapeutic compound has shown to be safe in humans and effective in lowering MMP-9 levels in treated patients (253, 254), with some neuroprotective effects (255), but it does not yield firm evidence on HT prevention