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In addition, simplified dosing regimens and reduced administration constraints are expected to improve treatment adherence and expand adoption across a broader patient population, strengthening the competitive position of oral therapies within the metabolic disease treatment landscape

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doi:10.1056/NEJMoa2416394 Harbi M, Ashour A, Alorfi N, et al

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Similarly, investigations in models of gastric ulceration and inflammatory bowel disease have demonstrated meaningful mucosal protective and healing effects

However, weight loss is not always satisfactory and is often not maintained over time, indicating that continual research is needed