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Relevant to many preclinical studies are the extensive investigations in male C57BL/6 mice that are summarized in Table 1 and compared with the data from insulin-resistant humans, because many cancer patients are also insulin resistant

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200 Thus, an insulin-mediated effect of diazoxide was proven

This can have profoundly important effects

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Prevention of contrast-induced nephropathy (CIN), usually defined as an increase of 25% in the serum creatinine level from baseline, is crucial because even small changes in renal function are associated with increased morbidity and mortality [176]