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The single-cell transcriptomic analysis of GA patients revealed that the encoding gene, HIF-1A, is significantly upregulated in the monocytes of GA patients (103)

HPLC Purification step

Significantly, vitamin B12 concentrations imply the levels of vitamin B12 in the circulation, and higher levels of serum vitamin B12 may not be directly caused by a higher intake, instead the dysregulation of the metabolism of this vitamin may contribute to higher levels of vitamin B12 in the circulation

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