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[13] In a newly diagnosed vitamin B 12 -deficient patient, normally defined as when serum levels are less than 200 pg/ml, daily IM injections of hydroxocobalamin up to 1,000 g (1 mg) per day are given to replenish the body's depleted cobalamin stores

It is recommended that CTS be considered not only as an important component of the management of inflammatory activity associated with RA, but also as a standalone element throughout the course of RA treatment

doi:10.3390/nu14153096

Even at low doses, these medications carry risks including pancreatitis (requiring discontinuation if suspected), gallbladder disease, and rare but serious adverse events such as medullary thyroid carcinoma (boxed warning

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