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What it does is reduce local inflammation, support the maintenance of remaining tissue, and in some cases improve synovial health in a way that changes the pain experience meaningfully

How and where it is sold usually determines access requirements

Refrigerating unopened vials offers no preservation benefit and may create condensation that obscures lot numbers or loosens labels

Our bodies do not create vitamin B12, it is obtained from food sources

However, potential side effects can include: Nausea or dizziness (rare) Headaches Injection site irritation Overstimulation or fatigue if overdosed There are no long-term human trials, so effects on hormones, organs, or chronic use remain unknown

Eric Topol, a research methods expert and director of Scripps Research Translational Institute