switched from semaglutide to tirzepatide Wondering what the dosage conversion is for tirzepatide? Dr Weiss looks at the SURPASS 2 trial to provide a guide. #joinfridays #wegovy #zepbound Switching from Tirzepatide to Semaglutide:

To make it clearer, our team put together a quick comparison

It is not known if GLP-1 passes into your breast milk Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements

Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism

Are you looking to lose weight and are B12 deficient

Patient monitoring should include: Baseline lipid panel, hemoglobin A1c, and liver function tests Blood pressure monitoring (GLP-1 agents typically reduce systolic BP by 3-5 mmHg) [10] Assessment for gastrointestinal adverse effects during dose titration Evaluation for contraindications (personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2) [1] [3] Monitoring for gallbladder disease (increased risk with rapid weight loss) In patients with diabetes and retinopathy, monitoring for worsening eye symptoms, particularly with rapid glycemic improvement Renal function assessment, especially if severe gastrointestinal symptoms cause dehydration Patients should seek immediate medical attention for severe abdominal pain, which may indicate pancreatitisa rare but serious adverse effect

For adolescent boys, the results are more complex with a third wanting to lose weight and another third hoping to bulk up with muscle