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The proportion of patients achieving at least 5% of clinically significant weight loss ranges from 37% to 47% for Lorcaserin, 35% to 73% for Orlistat, and 67% to 70% for the higher dose Of Phentermine plus extended release Topiramate

Tirzepatide is unique because it acts on two hormones, GLP-1 and GIP (glucose-dependent insulinotropic polypeptide)

The QoL level is similarly lower in euthymic depressed people, and this can be impacted by mental abilities, clinical symptoms, and social factors

Resistance training and adequate protein are often discussed, but targets should be individualized

This can create financial and logistical challenges for families and individuals trying to adhere to the diet[102]

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