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Setting realistic expectations helps maintain adherence during the initial period when side effects may be most prominent

Its important to understand how these treatments work, and what the evidence shows regarding their role in weight loss

Clinicians should conduct a thorough baseline assessment before initiating semaglutide in MS patients, including: Evaluation of current MS disease activity and disability status Assessment of gastrointestinal function and neurogenic bowel symptoms Review of concurrent medications, particularly MS treatments Screening for diabetic retinopathy if diabetes is present (semaglutide may increase risk of diabetic retinopathy complications) [9] [23] Renal function assessment Thyroid examination and history of thyroid disorders Patients should be counseled about the importance of maintaining adequate hydration and reporting any worsening of pre-existing MS symptoms

Most patients can continue semaglutide before elective surgery with appropriate risk assessment

Begin semaglutide therapy with a proactive hydration plan (100+ ounces of water daily), regular intake of potassium-rich foods, and magnesium glycinate supplementation (check dosing with your provider)

Obesity is a chronic disease