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Las pilas son solo para diseo experimental
(PubMed) Rude RK, Shils ME
Cutting technique (Extended Mohler) Mohler's technique was modified by Cutting who moved the upper end of the incision to just beyond the midline of the columella (about 4/7th of the width on the noncleft side), and extended the backcut down to the noncleft philtral column [25]
A Phase 2 randomised controlled trial published in The New England Journal of Medicine in 2023 (Jastreboff et al.) enrolled 338 adults with obesity and reported mean body weight reductions of up to approximately 24% over 48 weeks at the highest dose studied (12 mg weekly)
Some individuals may experience gastrointestinal issues, skin rashes, headaches, or respiratory problems, particularly with inhaled forms
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