Likewise, the overexpression of SOD is children with Down syndrome leads to a reduction of GSH and an increase in oxidative stress [13]
However, we feel that our robust study design achieved our study goals in a challenging, well-defined population of preschool children
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It features two distinct structural modifications: the substitution of a Glutamic acid for an Arginine at position 3 (hence Arg3), and a 13-amino-acid extension piece at the N-terminus (hence Long)