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Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions

Results BPC-157 accelerates wound closure in alkali-burned rats During the study, no abnormalities were observed in the general condition and behavior of rats in all treatment cohorts, including asitia, nausea, diarrhea, cough, or weight loss, and no symptoms of allergic response such as hydroposia or localized rash occurred in animals receiving bFGF or BPC-157

Typhimurium infection

Shi S, Lei S, Tang C, Wang K, Xia Z (2019) Melatonin attenuates acute kidney ischemia/reperfusion injury in diabetic rats by activation of the SIRT1/Nrf2/HO-1 signaling pathway

Faster escalation tends to increase side effects without improving the timeline to therapeutic effect

There is little risk of serious side effects with peptides