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Together, these discoveries firmly establish CoQ 10 oxidoreductases as a critical antiferroptotic defense system

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These pathways may exhibit crosstalk and collectively form complex regulatory networksan important area warranting deeper investigation in future studies

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As such, pharmacological modulation of ferroptosis, via both its induction and its inhibition, holds great potential for the treatment of drug-resistant cancers, ischaemic organ injuries and other degenerative diseases linked to extensive lipid peroxidation

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