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Preclinical Research on GHK-Cu and Cellular Regeneration Preclinical research on GHK-Cu explores fibroblasts, collagen, glycosaminoglycans, angiogenesis, inflammation, matrix metalloproteinases, tissue inhibitors, and wound models [4], [5], [10], [12]

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Sex was entered as the treatment of the mediation and Cortisol/11-deoxycortisol ratio as the mediator

However, the IM route was the top-ranked statistically but without clinical significance