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On the other hand, GSH and 2-mercaptoethanol displayed similar potency, needing thiol:AX ratios above 4:1 to obtain a complete abolition of antibiotic effects ( Figures 6B, C )

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First, it is able to accumulate specifically in tumor cells, remaining unaffected by MRP while maintaining good cell-membrane permeability

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Specifically, arachidonic acid (AA) and adrenoic acid (AdA) are dienophiles that are susceptible to oxidation by lipoxygenase (LOX), generating AA-PE-OOH or AdA-PE-OOH [59, 60]