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Compared to twice-daily preclinical dosing with the GLP-1 analogue liraglutide, once-weekly dosing of ZP4982 at almost equimolar doses was superior in terms of body weight loss in an obese rat model (143)

Mechanistic summaries on this page are provided for laboratory reference and should be interpreted within controlled experimental settings only. In preclinical models, AOD-9604 has demonstrated significant effects on body composition and adipose tissue metabolism

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New Engl J Med 388 , 921 (2022)