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This difference exists because charging too fast can be more damaging than discharging, especially if heat management isnt optimal

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Over the following 6 to 8 days, the concentration gradually declines as your body metabolizes the compound, primarily through hepatic pathways that do not interact with cytochrome P450 enzymes

FDA Fast Track designation for tirzepatide for the treatment of adults with obesity, or overweight with weight-related comorbidities. GLP duration in the body: Frontiers in Endocrinology (2019)

doi: 10.1016/j.psychsport.2024.102614, 58

Katoulis et al., 2014