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Inflammation and oxidative stress inhibition: GLP-1RA protects myocardial and renal cells from damage caused by energy metabolism disorders by inhibiting the NF - B pathway and NADPH oxidase activity, reducing the production of inflammatory factors such as IL-6, TNF - , and reactive oxygen species (ROS)

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& Conlon, J

Data from designated brain regions from the cFOS 3D brain imaging study were analysed using one-way ANOVA with Dunnets post hoc multiple-comparison test relative to the vehicle, using a negative binomial generalized linear model to control for Gaussian distribution

No human clinical trials of Dihexa itself published as of 2026

106 , e442e459 (2021)