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observed that supplementation with LC (250 mg oral L-carnitine supplementation for 12 weeks) leads to a significant reduction in body weight, body mass index and waist and hip circumference decreasing blood glucose levels and favors the contrast of insulin resistance [73], which may be attributed to the increase in -oxidation of fatty acids and the metabolic rate base line induced by LC [74]

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Furthermore, AST/Bex enhanced A clearance to the apical/plasma side in the in vitro model of the blood-brain barrier

The chronic nature of DM, coupled with the often-delayed onset of complications, may lead patients to underestimate the severity of their condition

Final data visualizations were generated using GraphPad Prism 10.0 (GraphPad Software, San Diego, CA, USA)