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Pain hypersensitivity is the consequence of early posttranslational changes, both in the peripheral terminals of the nociceptor and in dorsal horn neurons, as well as later transcription-dependent changes in effector genes, again in primary sensory and dorsal horn neurons (4)
Thats why leaky gut is often associated with symptoms such as brain fog, difficulting concentrating, and even mood issues
They can assess whether supplementation is necessary, review your dietary intake, and check baseline B12 levels if deficiency is suspected
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