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this did not affect the number of mtDNA mutations or the frequency of mutated genes in oocytes from 3-week- and 9-month-old mice, suggesting that an increase in oxidative stress in the mitochondrial matrix of oocytes does not lead to a significant increase in mtDNA mutations [45]

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Notably, tau protein lactylation at K677 initiates ferroautophagy and ferroptosis through the MAPK pathway, leading to microglial activation and neuroinflammation [82]