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Collagen production requires glycine in a 1:3 ratio with other amino acids in the collagen structure

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The addition of pyridoxine should not significantly affect the shelf life of the compound

Recent studies have shown high levels of vitamin B12 in the pilosebaceous follicle, and demonstrated that Vit B12 supplementation in Propionibacterium acnes colonies promotes the production of porphyrins which undergo a process of oxidation on the skin surface, release pro-inflammatory substances that ultimately favor the development of acneiform lesions [7]

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