These doses are well tolerated and have no meaningful toxicity risk, as excess B12 is excreted in urine rather than accumulating in tissues
It works closely with folate, another B vitamin, and they depend on each other for activation, so they can carry out their necessary functions in the body
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According to two studies analysing the evidence on B12 in plant-based foods, only the seaweeds hijiki, nori and chlorella, mushrooms, a few non-common plants and a type of fermented soya yoghurt contained some all due to bacterial activity but amounts vary with some of the samples containing no B12 (Watanabe and Bito, 2018
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Diagnosis can be made by ordering laboratory blood tests