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Common reasons for failure include uneven fat removal, which can lead to contour irregularities or an uneven distribution of fat, and skin sagging when too much fat is removed

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Diarrhea usually mild and goes away within the first few weeks

What is more, no clear trend for a change in pharmacokinetics was evident across groups with increasing renal dysfunction 12 that allowed us to administer the same dose of the drug and the same blood sampling time points in patients with different degree of renal impairment who were included in our study

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