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However, because they reduce appetite and slow digestion, they might make it harder to get all the nutrients your body needs

Clin Immunol (2014) 155(2):2139

Metabolic adaptation is most likely the reason for this plateau [11] rather than poor response or resistance to the medication

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The rate-limiting enzyme of glutathione synthesis, -glutamylcysteine synthetase (GCS), is composed of a catalytic (GCS-HS) and regulatory subunit (GCS-LS)

Hypokalemia Like other types of insulin, Tresiba may cause low blood potassium levels (hypokalemia)