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Increased efflux of GSH in PfMRP1 mutant parasites decreased thiol levels and enhanced artemisinin sensitivity, while increasing reduced GSH levels with NAC decreased artemisinin potency

This must include awareness that symptoms of acidosis may overlap with gastrointestinal (GI) side effects of GLP-1 and GLP-1/GIP RA therapy

Fukami A, Seino Y, Ozaki N et al (2013) Ectopic expression of GIP in pancreatic -cells maintains enhanced insulin secretion in mice with complete absence of proglucagon-derived peptides

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Polycystic ovary syndrome (PCOS) exemplifies this

When the mitochondria cannot efficiently import and burn long-chain fatty acids due to membrane damage or carnitine depletion, the body is forced to rely on less efficient, anaerobic pathways for energy production