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4.3 Translational DoseResponse Considerations and Human Attainability While numerous in vitro studies report IC 50 values demonstrating anti-proliferative or pro-apoptotic activity of natural compounds in breast cancer cell lines, the clinical relevance of these concentrations requires careful evaluation

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Wang P, Cui Y, Ren Q, Yan B, Zhao Y, Yu P, Gao G, Shi H, Chang S, Chang YZ (2021b) Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis

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Because our acetaminophen model is connected to our GSH model we can compute these time courses explicitly