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Results FoB and MZB exhibit distinct glutathione-based redox dependencies To dissect the redox state of MZB and FoB in relation to the main antioxidant GSH, we studied the expression of Gclc , which is necessary for GSH synthesis 24 , in isolated MZB and FoB from spleens of C57BL/6J (B6 or wild-type) mice

increasing the dose did not yield proportional gains, underscoring the importance of optimisation rather than maximisation [182]

Current dose is 0.5 mg weekly after 4 weeks at 0.25 mg

The prognosis of cyclical vomiting syndrome

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