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When pathogens are detected, through mechanisms like pathogen-associated molecular patterns (PAMPs), damage-associated molecular patterns (DAMPs), or through detection of pathogen toxins, mucus-producing cells can dramatically increase mucin production and secretion (Rada et al., 2011

Further, the absolute risk reduction is small, which translates into a comparatively high number needed to treat of 67

Note that 2/3 of the weight lost by the participants was regained within a year of stopping treatment with semaglutide

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Lau DC, Erichsen L, Francisco AM, Satylganova A, le Roux CW, McGowan B, et al