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Vasculogenic ED in particular is linked with arterial and endothelial damage, often attributed to systemic inflammation

doi: 10.1146/annurev-cancerbio-070824-125326 228 MacDonaldWJPurcellCPinho-SchwermannMStubbsNMSrinivasanPREl-DeiryWS

The first model, mouse alveolar macrophage cell line MH-S, is representative of resident professional phagocytes in the lungs and is considered appropriate for pulmonary toxicological and immunological studies

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For example, the ROS hydrogen peroxide, which reduced glutathione directly neutralizes, is a form of ROS that also causes significant inflammation in the body