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Upon activation of PI3K/AKT cue, activated PI3K phosphorylates and activates AKT, with consequent activation of cyclic adenosine monophosphate (CAMP) response element-binding protein (CREB), which enhances the generation of BDNF (Luo et al
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Biphasic activation of apoptosis signal-regulating kinase 1-stress-activated protein kinase 1-c-Jun N-terminal protein kinase pathway is selectively mediated by Ca2 + -permeable -amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors involving oxidative stress following brain ischemia in rat hippocampus
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