The starting dose (2mg) is for tolerance, not efficacy
however, its effect on prevention is less pronounced than T1DM
Start your intake How GLP-1 Medications Support Intermittent Fasting Success GLP-1 drugs slow gastric emptying and increase satiety signals, which can make longer fasting windows feel more sustainable than diet alone
The guide says medical literature suggests roughly 20 to 22 percent weight loss at 2.4 mg weekly against 10 to 15 percent at lower amounts, but names no trial or publication
Ping P, Murphy E: Role of p38 mitogen-activated protein kinases in preconditioning: a detrimental factor or a protective kinase
Front Cell Infect Microbiol 10:572912 Rauch I, Deets KA, Ji DX et al (2017) NAIP-NLRC4 inflammasomes coordinate intestinal epithelial cell expulsion with eicosanoid and IL-18 release via activation of caspase-1 and -8