Finer than 27 gauge should not be used, because of the danger of it breaking whilst in your flesh
In published metabolic and longevity research, 5-Amino-1MQ is often referenced alongside other compounds investigated for energy-expenditure, NAD+ and methyl-pool research
Workable but cumbersome
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This, in turn, can result in B12 deficiency
Neelakantan and colleagues (Biochem Pharmacol, 2018) reported that 1-methylquinolinium and 1-methylnicotinamide showed no measurable passive diffusion in their assays, whereas 5-amino-1MQ crossed by both passive and active routes with no detectable efflux in Caco-2 cells, and lowered intracellular 1-methylnicotinamide in differentiated 3T3-L1 adipocytes with an EC near 2.3 M