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2011 Aug;103(4):349-57

Ideal candidates for Rybelsus weight loss treatment include: Adults with type 2 diabetes and BMI over 27 Patients who have difficulty with injectable medications Individuals seeking combined glucose and weight management Those who have not achieved goals with other diabetes medications The medication is not recommended for patients with type 1 diabetes, diabetic ketoacidosis, or those with a family history of medullary thyroid carcinoma

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Digestive Issues Women with Lipedema already have higher rates of: IBS Constipation Bloating SIBO (small intestinal bacterial overgrowth) Slow digestion GLP-1s slow gastric emptying even further, which can increase: Constipation Gastroparesis Reflux Nausea If digestive issues are present, they ideally should be addressed before starting GLP-1s

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