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In the tirzepatide trial, participants lost an average of 6.9% of their weight after 12 weeks, while retatrutide participants lost 7.2% at the lowest dose after 24 weeks

The medication also carries a well-established cardiovascular benefit in those with type 2 diabetes, having demonstrated a reduction in major cardiovascular events in the landmark LEADER trial

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A., Williams, L., Bork, P., Bridge, A., Gough, J., Haft, D

It counteracts damage from NSAIDs by working independently of the prostaglandin pathway