Psychostimulants, such as methamphetamine, cocaine and synthetic cathinones, disrupt monoaminergic neurotransmission, causing cognitive impairment, psychiatric disturbances, and neurovascular damage
Regulatory effects of transporters on drug accumulation and tissue distribution Transmembrane transporters are the core molecules regulating the cellular uptake and efflux of platinum-based agents, which influence the accumulation levels of the agents in tumor cells and normal target organs, thereby affecting chemotherapy efficacy and toxicity risk
First, shinorine biosynthetic genes from cyanobacterium Nostoc punctiform were introduced into S
This bioavailable form of L-carnitine efficiently crosses the bloodbrain barrier to promote mitochondrial energy productionfueling optimal mental performance and cellular vitality
Oct 1994;14(10):1625-1630
To identify ACSL isoforms that contribute to ESA-induced ferroptosis, we individually knocked down expression of each of the five isoforms in BT-549 and MDA-MB-231 cells by RNAi (Supplementary Fig
