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Methods to deliver iron chelators to the CNS include direct (such as intranasal and intrathecal) and indirect (such as oral and injections) routes (Figure 1) (Rohani et al., 2017

Sourcing high-quality, stable glutathione and ensuring consistent potency in finished products present ongoing formulation hurdles

Since it interacts with the bodys natural hormonal and neurological systems, individual responses may vary significantly

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Particularly, the induced depletion of GSH in organs of adult animals was greater than previously observed depletions using pharmacologic approaches 19