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The application was shortly after anastomosis injury, intraperitoneal or intragastric or local, at the site of anastomosis

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In conclusion, the use of melatonin as an adjunctive therapy for sepsis treatment significantly reduced inflammatory biomarkers and improved clinical conditions in neonates, but larger scale studies with higher validity are needed to demonstrate clear clinical benefits of the therapy 103,105,107,108,109

SFN reduces the expression of adipogenic factors such as PPAR and CCAAT/enhancer-binding protein (C/EBP), which inhibits adipocyte formation and fat accumulation