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Furthermore, its efficacy is limited, reducing grade 2 acute xerostomia from 78% to 51% ( p 90%) of lyophilized macromer was determined by 1 H-NMR: 4-arm PEG-amine norbornene ( 1 H NMR (CDCl 3 ): d = 6.06.3 ppm (norbornene vinyl protons, 8H, multiplet), 3.53.9 ppm (PEG ether protons, 1817H, multiplet))

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Factors such as genetics, body chemistry and caffeine-consuming habits indicate whether someone is a fast metabolizer or slow metabolizer of caffeine