Efficiency in Comparative Trials
Tirzepatide works by: Slowing gastric emptying , which prolongs the feeling of fullness after meals Reducing appetite through effects on brain centres that regulate hunger Improving insulin secretion in response to elevated blood glucose Decreasing glucagon secretion , which helps lower blood sugar levels Clinical trials have demonstrated that tirzepatide can lead to substantial weight losswith dose-dependent reductions of approximately 1520% of body weight over 72 weekswhen combined with lifestyle modifications
The effect may be particularly marked for women with polycystic ovarian syndrome, or PCOS
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Am Heart J 1989;117:91 Chobanian AV, Bakris GL, Black HR, et al